Oncology
Oncology

Colorectal Cancer: Symptoms, Causes, Treatment and Survival rate

Colorectal cancer is one of the most common cancers worldwide. It is an abnormal growth of cells arising from the colon (large intestine) and rectum.

Colorectal cancer symptoms

Recognizing the symptoms of colorectal cancer is crucial for early detection and treatment. Here, we’ll discuss these symptoms in simple language to help you understand what to look out for.

One common symptom of colorectal cancer is changes in bowel habits. This can include experiencing diarrhea or constipation that lasts for more than a few days. You may also feel like your bowel doesn’t empty completely after a bowel movement. If you notice persistent changes in your bathroom routine, it’s important to talk to your healthcare provider.

Another symptom to watch for is blood in the stool. If you see blood in your stool or notice bloody streaks on toilet paper after wiping, it could be a sign of colorectal cancer. However, it’s essential to remember that not all cases of rectal bleeding are due to cancer. Conditions like hemorrhoids can also cause bleeding. Still, it’s crucial to get any bleeding checked by a healthcare professional.

Some people with colorectal cancer may experience abdominal discomfort. This can manifest as cramps, bloating, gas, or pain in the abdomen. Even after bowel movements or changes in diet, this discomfort may persist. While these symptoms can indicate various conditions, it’s important to pay attention if they are persistent or worsening.

Unexplained weight loss is another potential symptom of colorectal cancer. If you find yourself losing weight without trying or making changes to your diet or exercise routine, it could be a cause for concern. Significant and unexplained weight loss, especially when combined with other symptoms like changes in bowel habits or abdominal discomfort, should prompt a visit to your healthcare provider.

Fatigue and weakness are symptoms that can accompany colorectal cancer, especially as the cancer progresses. If you feel persistently tired, weak, or fatigued even with adequate rest, it’s important to discuss these symptoms with your doctor. Cancer can cause changes in the body that lead to fatigue, so it’s crucial not to ignore these feelings.

Colorectal cancer can also lead to iron deficiency anemia over time due to slow, chronic bleeding. Symptoms of anemia include fatigue, weakness, pale skin, dizziness, and shortness of breath. If you experience these symptoms along with other colorectal cancer symptoms, it’s crucial to seek medical evaluation promptly.

Changes in stool consistency can also be a sign of colorectal cancer. This can include stools that are narrower than usual (often described as pencil-thin stools) or changes in texture or appearance. While occasional changes in stool are normal, persistent changes should be discussed with your healthcare provider.

In advanced cases of colorectal cancer, a tumor may grow large enough to block the bowel partially or completely, leading to bowel obstruction. This can cause severe abdominal pain, cramping, bloating, nausea, vomiting, and the inability to pass gas or stool. Bowel obstruction is a medical emergency and requires immediate medical attention.

Colorectal cancer causes

understanding about the causes and risk factors can help an individual categorize its own risk and help him seek early medical attention.

Genetic factors can significantly impact an individual’s likelihood of developing colorectal cancer. Inherited gene mutations, such as those associated with Lynch syndrome or familial adenomatous polyposis (FAP), can increase the risk. Additionally, having a family history of colorectal cancer or certain genetic conditions can also predispose individuals to this type of cancer. Genetic testing and understanding one’s family medical history can help identify individuals at higher risk.

Lifestyle choices also play a significant role in colorectal cancer risk. A diet high in red and processed meats, along with low fiber intake from fruits, vegetables, and whole grains, is linked to an increased risk of colorectal cancer. Obesity, especially carrying excess weight around the waist, is another risk factor. Lack of regular physical activity or a sedentary lifestyle can further contribute to colorectal cancer risk.

Age and gender are also important factors to consider. Colorectal cancer is more common in individuals aged 50 and older, although cases can occur at younger ages. Men tend to have a slightly higher risk of developing colorectal cancer compared to women. Regular screening for colorectal cancer is typically recommended starting at age 50 for average-risk individuals, or earlier for those with additional risk factors.

Chronic inflammation in the digestive tract, as seen in conditions like ulcerative colitis and Crohn’s disease (collectively known as inflammatory bowel diseases or IBD), can increase the risk of colorectal cancer over time. Managing and treating these inflammatory conditions effectively is crucial in reducing cancer risk.

Certain lifestyle habits can also contribute to colorectal cancer risk. Smoking tobacco, including cigarettes, has been linked to an increased likelihood of developing colorectal cancer. Heavy alcohol consumption over a prolonged period is another risk factor. Quitting smoking and moderating alcohol intake can have significant benefits in reducing cancer risk and improving overall health.

Individuals with type 2 diabetes or insulin resistance may have a higher risk of colorectal cancer, although the exact mechanisms are still being studied. It is essential for individuals with these conditions to manage their health effectively through lifestyle modifications and medical treatment as prescribed by healthcare providers.

Colorectal cancer Treatment

Knowing about the colorectal cancer treatment and staying uptodate with its newer modalities is crucial for getting the best treatment results.

Colorectal cancer treatment has advanced significantly in recent years, offering more effective options for managing the disease. Here are some of the latest and most effective treatment modalities:

1. Surgery: Surgery remains a cornerstone in treating colorectal cancer, especially for early-stage tumors. Minimally invasive techniques such as laparoscopic and robotic surgery help reduce recovery time and improve outcomes.

2. Chemotherapy: Chemotherapy uses drugs to kill cancer cells or stop them from growing. Newer chemotherapy drugs and targeted therapies are better at targeting cancer cells while minimizing damage to healthy cells, leading to improved outcomes and fewer side effects.

3. Immunotherapy: Immunotherapy is a groundbreaking treatment that helps the body’s immune system fight cancer cells. Drugs like immune checkpoint inhibitors have shown promising results in certain colorectal cancer cases, particularly those with specific genetic mutations.

4. Targeted Therapy: Targeted therapy drugs are designed to attack specific abnormalities within cancer cells. For colorectal cancer, targeted therapies like anti-EGFR drugs and anti-VEGF drugs can be highly effective, especially when combined with other treatments.

5. Radiation Therapy: Radiation therapy uses high-energy beams to kill cancer cells. Advanced techniques such as intensity-modulated radiation therapy (IMRT) and proton therapy help deliver precise radiation doses to tumors while sparing nearby healthy tissues.

6. Precision Medicine: Precision medicine involves tailoring treatment plans based on a person’s unique genetic makeup and tumor characteristics. Molecular testing helps identify specific genetic mutations or biomarkers, allowing doctors to prescribe targeted therapies that are most likely to be effective for individual patients.

Colorectal cancer treatment often involves a multidisciplinary team of specialists, including surgeons, medical oncologists, radiation oncologists, genetic counselors, and nutritionists. This collaborative approach ensures comprehensive care and personalized treatment plans for each patient.

Colorectal Cancer Survival Rate

For colorectal cancer, survival rates can vary based on several factors such as the stage of cancer at diagnosis, the patient’s overall health, and the effectiveness of treatment.

On average, the overall five-year survival rate for colorectal cancer is around 65% to 70%. This means that about 65% to 70% of people diagnosed with colorectal cancer will survive for at least five years after their diagnosis. However, it’s crucial to note that survival rates can vary widely depending on the stage of cancer. For example:

  • Early-stage colorectal cancer (Stage I and II) generally has higher survival rates, often above 90%.
  • Advanced-stage colorectal cancer (Stage III and IV) may have lower survival rates, especially if the cancer has spread to other organs.

Advancements in medical treatments, including surgery, chemotherapy, targeted therapy, and immunotherapy, have improved survival rates for colorectal cancer patients. Additionally, early detection through regular screenings such as colonoscopies can lead to better outcomes by catching the cancer at an earlier, more treatable stage. It’s important for individuals to discuss their specific prognosis and treatment options with their healthcare team based on their unique circumstances and cancer stage.

In conclusion, knowing about the various aspects of colorectal cancer, its causes, symptoms and various treatment modalities can help you identify your own risk and seek medical attention at the earliest in case you encounter any such symptoms. consult your healthcare provider or Oncologist to know more about the disease.

Dr. Ashwani Kumar Sachdeva is a distinguished oncologist based in Chandigarh with over a decade of experience in various oncological surgeries. His extensive expertise covers cancers across multiple systems, including Head & Neck, Breast, Thoracic,…

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